To conduct a systematic scoping review of explainable artificial intelligence (XAI) models that use real-world electronic health record data, categorize these techniques according to different biomedical applications, identify gaps of current studies, and suggest future research directions.
Rat Acetylcholinesterase (AchE) ELISA Kit |
RD-AchE-Ra-48Tests |
Reddot Biotech |
48 Tests |
EUR 534 |
Rat Acetylcholinesterase (AchE) ELISA Kit |
RD-AchE-Ra-96Tests |
Reddot Biotech |
96 Tests |
EUR 742 |
Human Acetylcholinesterase (AchE) ELISA Kit |
DLR-AchE-Hu-48T |
DL Develop |
48T |
EUR 498 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Acetylcholinesterase (AchE) in samples from serum, plasma, tissue homogenates or other biological fluids. |
Human Acetylcholinesterase (AchE) ELISA Kit |
DLR-AchE-Hu-96T |
DL Develop |
96T |
EUR 647 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Acetylcholinesterase (AchE) in samples from serum, plasma, tissue homogenates or other biological fluids. |
Mouse Acetylcholinesterase (AchE) ELISA Kit |
DLR-AchE-Mu-48T |
DL Develop |
48T |
EUR 508 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Acetylcholinesterase (AchE) in samples from serum, plasma, tissue homogenates or other biological fluids. |
Mouse Acetylcholinesterase (AchE) ELISA Kit |
DLR-AchE-Mu-96T |
DL Develop |
96T |
EUR 661 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Acetylcholinesterase (AchE) in samples from serum, plasma, tissue homogenates or other biological fluids. |
Rat Acetylcholinesterase (AchE) ELISA Kit |
DLR-AchE-Ra-48T |
DL Develop |
48T |
EUR 528 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Rat Acetylcholinesterase (AchE) in samples from serum, plasma, tissue homogenates or other biological fluids. |
Rat Acetylcholinesterase (AchE) ELISA Kit |
DLR-AchE-Ra-96T |
DL Develop |
96T |
EUR 690 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Rat Acetylcholinesterase (AchE) in samples from serum, plasma, tissue homogenates or other biological fluids. |
Human Acetylcholinesterase (AchE) ELISA Kit |
RDR-AchE-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 522 |
Human Acetylcholinesterase (AchE) ELISA Kit |
RDR-AchE-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 724 |
Mouse Acetylcholinesterase (AchE) ELISA Kit |
RDR-AchE-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 534 |
Mouse Acetylcholinesterase (AchE) ELISA Kit |
RDR-AchE-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 742 |
Rat Acetylcholinesterase (AchE) ELISA Kit |
RDR-AchE-Ra-48Tests |
Reddot Biotech |
48 Tests |
EUR 558 |
Rat Acetylcholinesterase (AchE) ELISA Kit |
RDR-AchE-Ra-96Tests |
Reddot Biotech |
96 Tests |
EUR 776 |
ACHE Antibody |
1-CSB-PA001154EA01BO |
Cusabio |
|
|
|
Description: A polyclonal antibody against ACHE. Recognizes ACHE from Bovine. This antibody is Unconjugated. Tested in the following application: ELISA |
ACHE Antibody |
1-CSB-PA001154GA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against ACHE. Recognizes ACHE from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB |
ACHE Antibody |
1-CSB-PA010202 |
Cusabio |
|
|
|
Description: A polyclonal antibody against ACHE. Recognizes ACHE from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/40000 |
ACHE Antibody |
1-CSB-PA010203 |
Cusabio |
|
|
|
Description: A polyclonal antibody against ACHE. Recognizes ACHE from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/5000 |
ACHE Antibody |
1-CSB-PA114463 |
Cusabio |
|
|
|
Description: A polyclonal antibody against ACHE. Recognizes ACHE from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
ache Antibody |
1-CSB-PA863598LA01DIL |
Cusabio |
|
|
|
Description: A polyclonal antibody against ache. Recognizes ache from Zebrafish. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:500-1:5000 |
ACHE Antibody |
1-CSB-PA904467 |
Cusabio |
|
|
|
Description: A polyclonal antibody against ACHE. Recognizes ACHE from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:1000-1:2000, WB:1:200-1:1000 |
ACHE Antibody |
CSB-PA547258- |
Cusabio |
|
EUR 335 |
|
Description: A polyclonal antibody against ACHE. Recognizes ACHE from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000 |
ACHE Antibody |
CSB-PA547258-100ul |
Cusabio |
100ul |
EUR 316 |
|
Description: A polyclonal antibody against ACHE. Recognizes ACHE from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000 |
ACHE Antibody |
1-CSB-PA5619A0Rb |
Cusabio |
|
|
|
Description: A polyclonal antibody against ACHE. Recognizes ACHE from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200 |
AChE antibody |
22892-100ul |
SAB |
100ul |
EUR 390 |
AChE antibody |
22893-100ul |
SAB |
100ul |
EUR 390 |
ACHE Antibody |
34375-100ul |
SAB |
100ul |
EUR 252 |
ACHE Antibody |
34375-50ul |
SAB |
50ul |
EUR 187 |
ACHE siRNA |
20-abx900114 |
Abbexa |
|
|
|
ACHE siRNA |
20-abx906502 |
Abbexa |
|
|
|
ACHE siRNA |
20-abx906503 |
Abbexa |
|
|
|
ACHE Antibody |
AF5274 |
Affbiotech |
200ul |
EUR 304 |
Description: ACHE Antibody detects endogenous levels of total ACHE. |
ACHE Antibody |
DF3725 |
Affbiotech |
200ul |
EUR 304 |
Description: ACHE Antibody detects endogenous levels of total ACHE. |
AChE antibody |
10C-CR1317M1 |
Fitzgerald |
100 ug |
EUR 639 |
Description: Mouse monoclonal AChE antibody |
AChE antibody |
10C-CR6003M1 |
Fitzgerald |
100 ul |
EUR 639 |
Description: Mouse monoclonal AChE antibody |
AchE antibody |
10R-8565 |
Fitzgerald |
100 ul |
EUR 393 |
Description: Mouse monoclonal AchE antibody |
AChE antibody |
10R-A104a |
Fitzgerald |
200 ul |
EUR 673 |
Description: Mouse monoclonal AChE antibody |
ACHE Peptide |
45-193P |
ProSci |
0.1 mg |
EUR 338 |
Description: ACHE Peptide |
ACHE antibody |
70R-33979 |
Fitzgerald |
100 ug |
EUR 327 |
Description: Rabbit polyclonal ACHE antibody |
AChE antibody |
70R-12480 |
Fitzgerald |
100 ul |
EUR 457 |
Description: Affinity purified Rabbit polyclonal AChE antibody |
AChE antibody |
70R-12595 |
Fitzgerald |
100 ul |
EUR 457 |
Description: Affinity purified Rabbit polyclonal AChE antibody |
ACHE antibody |
70R-15540 |
Fitzgerald |
50 ul |
EUR 435 |
Description: Rabbit polyclonal ACHE antibody |
AChE antibody |
70R-6077 |
Fitzgerald |
50 ug |
EUR 467 |
Description: Rabbit polyclonal AChE antibody Yt blood group |
AChE antibody |
70R-6078 |
Fitzgerald |
50 ug |
EUR 467 |
Description: Rabbit polyclonal AChE antibody Yt blood group |
AChE antibody |
70R-49326 |
Fitzgerald |
100 ul |
EUR 244 |
Description: Purified Polyclonal AChE antibody |
Recombinant Acetylcholinesterase (AchE) |
4-RPB447Hu01 |
Cloud-Clone |
-
EUR 530.08
-
EUR 245.00
-
EUR 1712.80
-
EUR 637.60
-
EUR 1175.20
-
EUR 418.00
-
EUR 4132.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Human Acetylcholinesterase expressed in: E.coli |
Recombinant Acetylcholinesterase (AchE) |
4-RPB447Mu01 |
Cloud-Clone |
-
EUR 539.04
-
EUR 247.00
-
EUR 1746.40
-
EUR 648.80
-
EUR 1197.60
-
EUR 424.00
-
EUR 4216.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Mouse Acetylcholinesterase expressed in: E.coli |
Recombinant Acetylcholinesterase (AchE) |
4-RPB447Mu02 |
Cloud-Clone |
-
EUR 539.04
-
EUR 247.00
-
EUR 1746.40
-
EUR 648.80
-
EUR 1197.60
-
EUR 424.00
-
EUR 4216.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Mouse Acetylcholinesterase expressed in: E.coli |
Recombinant Acetylcholinesterase (AchE) |
4-RPB447Ra01 |
Cloud-Clone |
-
EUR 539.04
-
EUR 247.00
-
EUR 1746.40
-
EUR 648.80
-
EUR 1197.60
-
EUR 424.00
-
EUR 4216.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Rat Acetylcholinesterase expressed in: E.coli |
Recombinant Acetylcholinesterase (AchE) |
4-RPB447Ra02 |
Cloud-Clone |
-
EUR 539.04
-
EUR 247.00
-
EUR 1746.40
-
EUR 648.80
-
EUR 1197.60
-
EUR 424.00
-
EUR 4216.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Rat Acetylcholinesterase expressed in: E.coli |
Bovine Acetylcholinesterase (ACHE) |
1-CSB-EP001154BO |
Cusabio |
-
EUR 611.00
-
EUR 309.00
-
EUR 1827.00
-
EUR 939.00
-
EUR 1218.00
-
EUR 397.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Bovine Acetylcholinesterase(ACHE) expressed in E.coli |
AChE Polyclonal Antibody |
ES6254-100ul |
ELK Biotech |
100ul |
EUR 279 |
Description: A Rabbit Polyclonal antibody against AChE from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
AChE Polyclonal Antibody |
ES6254-50ul |
ELK Biotech |
50ul |
EUR 207 |
Description: A Rabbit Polyclonal antibody against AChE from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
AChE Polyclonal Antibody |
ES6255-100ul |
ELK Biotech |
100ul |
EUR 279 |
Description: A Rabbit Polyclonal antibody against AChE from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA |
AChE Polyclonal Antibody |
ES6255-50ul |
ELK Biotech |
50ul |
EUR 207 |
Description: A Rabbit Polyclonal antibody against AChE from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA |
Anti-ACHE antibody |
STJ27933 |
St John's Laboratory |
100 µl |
EUR 277 |
Description: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. |
Anti-ACHE antibody |
STJ22483 |
St John's Laboratory |
100 µl |
EUR 277 |
Description: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. |
Anti-ACHE antibody |
STJ22484 |
St John's Laboratory |
100 µl |
EUR 277 |
Description: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. |
ACHE Q Antibody |
20-abx121005 |
Abbexa |
-
EUR 300.00
-
EUR 439.00
-
EUR 189.00
|
|
|
Acetylcholinesterase (AchE) Antibody |
20-abx110522 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Acetylcholinesterase (AchE) Antibody |
20-abx110745 |
Abbexa |
|
|
|
AChE Polyclonal Antibody |
ABP55255-003ml |
Abbkine |
0.03ml |
EUR 158 |
|
Description: A polyclonal antibody for detection of AChE from Human, Mouse, Rat. This AChE antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AChE |
AChE Polyclonal Antibody |
ABP55255-01ml |
Abbkine |
0.1ml |
EUR 289 |
|
Description: A polyclonal antibody for detection of AChE from Human, Mouse, Rat. This AChE antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AChE |
AChE Polyclonal Antibody |
ABP55255-02ml |
Abbkine |
0.2ml |
EUR 414 |
|
Description: A polyclonal antibody for detection of AChE from Human, Mouse, Rat. This AChE antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AChE |
AChE Polyclonal Antibody |
ABP55256-003ml |
Abbkine |
0.03ml |
EUR 158 |
|
Description: A polyclonal antibody for detection of AChE from Human, Mouse, Rat. This AChE antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human AChE at AA rangle: 520-600 |
AChE Polyclonal Antibody |
ABP55256-01ml |
Abbkine |
0.1ml |
EUR 289 |
|
Description: A polyclonal antibody for detection of AChE from Human, Mouse, Rat. This AChE antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human AChE at AA rangle: 520-600 |
AChE Polyclonal Antibody |
ABP55256-02ml |
Abbkine |
0.2ml |
EUR 414 |
|
Description: A polyclonal antibody for detection of AChE from Human, Mouse, Rat. This AChE antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human AChE at AA rangle: 520-600 |
Acetylcholinesterase (AchE) Antibody |
20-abx001246 |
Abbexa |
|
|
|
Acetylcholinesterase (AchE) Antibody |
20-abx004712 |
Abbexa |
-
EUR 411.00
-
EUR 592.00
-
EUR 314.00
|
|
|
Acetylcholinesterase (AchE) Antibody |
20-abx101930 |
Abbexa |
-
EUR 411.00
-
EUR 133.00
-
EUR 1149.00
-
EUR 565.00
-
EUR 314.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Acetylcholinesterase (AchE) Antibody |
20-abx101931 |
Abbexa |
-
EUR 425.00
-
EUR 133.00
-
EUR 1177.00
-
EUR 578.00
-
EUR 328.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Acetylcholinesterase (AchE) Antibody |
20-abx101932 |
Abbexa |
-
EUR 425.00
-
EUR 133.00
-
EUR 1177.00
-
EUR 578.00
-
EUR 328.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Acetylcholinesterase (AchE) Antibody |
20-abx101933 |
Abbexa |
-
EUR 328.00
-
EUR 815.00
-
EUR 425.00
-
EUR 154.00
-
EUR 258.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Acetylcholinesterase (AchE) Antibody |
20-abx101934 |
Abbexa |
-
EUR 439.00
-
EUR 133.00
-
EUR 1247.00
-
EUR 592.00
-
EUR 328.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Acetylcholinesterase (AchE) Antibody |
20-abx101935 |
Abbexa |
-
EUR 439.00
-
EUR 133.00
-
EUR 1247.00
-
EUR 592.00
-
EUR 328.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Acetylcholinesterase (AchE) Antibody |
abx034995-400ul |
Abbexa |
400 ul |
EUR 523 |
|
Acetylcholinesterase (AchE) Antibody |
abx034995-80l |
Abbexa |
80 µl |
EUR 286 |
|
ACHE Rabbit pAb |
A1454-100ul |
Abclonal |
100 ul |
EUR 308 |
ACHE Rabbit pAb |
A1454-200ul |
Abclonal |
200 ul |
EUR 459 |
ACHE Rabbit pAb |
A1454-20ul |
Abclonal |
20 ul |
EUR 183 |
ACHE Rabbit pAb |
A1454-50ul |
Abclonal |
50 ul |
Ask for price |
Acetylcholinesterase (AchE) Antibody |
20-abx005992 |
Abbexa |
-
EUR 411.00
-
EUR 592.00
-
EUR 182.00
-
EUR 314.00
|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
|
|
Acetylcholinesterase (AchE) Antibody |
20-abx009630 |
Abbexa |
-
EUR 300.00
-
EUR 439.00
-
EUR 189.00
|
|
|
Acetylcholinesterase (AchE) Antibody |
20-abx014143 |
Abbexa |
-
EUR 314.00
-
EUR 98.00
-
EUR 398.00
-
EUR 495.00
|
- 100 ug
- 10 ug
- 200 ug
- 300 µg
|
|
Acetylcholinesterase (AchE) Antibody |
abx025536-100ul |
Abbexa |
100 ul |
EUR 523 |
|
Acetylcholinesterase (AchE) Antibody |
abx033719-400ul |
Abbexa |
400 ul |
EUR 523 |
|
Acetylcholinesterase (AchE) Antibody |
abx033719-80l |
Abbexa |
80 µl |
EUR 286 |
|
ACHE Polyclonal Antibody |
A55190 |
EpiGentek |
100 µg |
EUR 570.55 |
Description: The best epigenetics products |
ACHE Rabbit pAb |
A6161-100ul |
Abclonal |
100 ul |
EUR 308 |
ACHE Rabbit pAb |
A6161-200ul |
Abclonal |
200 ul |
EUR 459 |
ACHE Rabbit pAb |
A6161-20ul |
Abclonal |
20 ul |
Ask for price |
ACHE Rabbit pAb |
A6161-50ul |
Abclonal |
50 ul |
EUR 223 |
ACHE Rabbit pAb |
A2806-100ul |
Abclonal |
100 ul |
EUR 308 |
We searched MEDLINE, IEEE Xplore, and the Association for Computing Machinery (ACM) Digital Library to identify relevant papers published between January 1, 2009 and May 1, 2019.
We summarized these studies based on the year of publication, prediction tasks, machine learning algorithm, dataset(s) used to build the models, the scope, category, and evaluation of the XAI methods. We further assessed the reproducibility of the studies in terms of the availability of data and code and discussed open issues and challenges.Forty-two articles were included in this review.